What is the Effector mechanism triggered by CD8 cells?
effector mechanisms of T lymphocytes CD8+ . After the recognition of cells -targeted via MHC class I (1), T lymphocytes CD8+ or cytotoxic agents can trigger apoptosis of the cell - target through the via the death receptors (2.
How does tcd8 cytotoxicity occur?
The first mechanism involves the formation of pores in the membranes and thus occurs the entry of ions and water into the cell. The second involves apoptosis, which is programmed cell death. For this to occur, the activated CD8+ T lymphocyte produces two proteins involved in this process. They are perforin and granzyme.
How does the standard Th2 response happen?
In a answer primary the cell Th2 first encounters the antigen presented by dendritic cells or macrophages. the cell Th2 “initiated” can then interact with B cells that have encountered antigen and are presenting peptides in association with MHC class II molecules.
Which cytokine is produced by Th2 cells?
cytokines originated from Th2 cells : Interleukin-4 (IL-4): produced per Th2 cells , cells CD4+ T, mast cells. It is a growth factor for cells B and cells T CD4+ Th2 , promotes the synthesis of IgE and IgG; inhibits cells T CD4+ Th1.
What is the role of helper T lymphocytes?
THE helper T lymphocyte , CD4+, has the occupation to coordinate the occupation of immune defense against viruses, bacteria and fungi, mainly through the production and release of cytokines and interleukins.